Cancer

Podcast: Medical news headlines don't always capture the facts

Podcast file: 

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The headlines don't bear out the content in two news items from late this week.

The first item is that periodontal disease treatment reverses the risk of premature birth.  There was no evidence, in the extremely limited amount of information presented in the press release, that investigators were blinded to whether the patients had a preterm delivery.  The decision of whether their periodontal disease treatment was successful was performed "post-hoc" so one can't rule out a bias in assessing a successful outcome.  We just don't know.

New prostate cancer drug set to announce results March 5

There are not too many drugs that improve overall survival in prostate cancer.  Right now, the list is pretty short: Taxotere.

So the announcement that researchers have survival improvement with a new drug, cabazitaxel, is pretty exciting for us oncologists.

It's easy to become discouraged, but once in a while we get something to be happy about.  Today is one of those moments.

Osteoporosis treatments to prevent breast cancer

Dr. Otis Brawley weighs in: ACS revises prostate cancer screening recommendations

Prostate cancer awareness postage stamp.Can anyone really be surprised?  I remember Dr. Brawley talking to us young fellows about the hazards of prostate cancer screening as far back as 2003.  As I recall, he was even mad that there was a prostate cancer postage stamp! 

Avastin is a miss in gastric cancer

Remember 2007?  That was the year Avastin was going to set the world on fire.  There was improved survival success in colon cancer, then lung cancer.  Avastin was on a tear.

Improved survival is an easy sell to the FDA.  The survival advantage wasn't huge, but it was statistically reproducible, and so the benefit of helping people with advanced cancer live longer made this new treatment attractive.

Cancer clinical trial drug offers hope...for some

NYT today has an excellent long narrative about the clinical trial drug PLX4032.  For some, the drug seems to work very well in eradicating metastatic melanoma.

David Agus weighs in on the future of cancer research

TED releases a video recorded in October 2009, in which famed oncologist David Agus reports what's wrong with cancer research, and how to fix it.

Bernadine Healy and the aspirin breast cancer study

Dr. Bernadine HealyDr. Healy is both a thoughtful, seasoned doctor and a health columnist for US News and World Report.  She was the prime motivator for the outstanding Womens' Health Initiative study, a project that continues to bear fruit to this day.

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