Sirolimus
Rapamycin enhances mouse longevity?
Submitted by Anonymous on Wed, 2009-07-08 16:41Paper in Nature this week shows impressive longevity gains with rapamycin an mTOR inhibitor. We use these drugs now to treat kidney cancer. http://feeds.wired.com/~r/wiredscience/~3/V7UA3NJ-ed4/ Big drawback to rapamycin: markedly increased risk of cancer. So perhaps a person would live longer only to develop some sort of tumor. Still an interesting and unexpected finding. By the way watch for rapamycin hype starting right away.
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Fourth drug approved for renal cell cancer
Submitted by Anonymous on Tue, 2009-03-31 16:01This is quoted from the ASCO email update circulated 3/31. We now have four drugs for renal cell cancer! The Wall Street Journal (3/31 Whalen) reports "The US Food and Drug Administration approved for sale a kidney-cancer drug that Novartis AG hopes to eventually expand to a variety of other cancers." Afinitor [everolimus] acts by targeting "a protein in the body that appears to underlie more than half a dozen types of cancer " the company stated.
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