WSJ today reports a fascinating piece that exposes the dark underbelly of clinical research. "Jonathan Leo a professor of neuro-anatomy at tiny Lincoln Memorial University in Harrogate Tenn. posted a letter on the Web site of the British Medical Journal this month criticizing a study that appeared in JAMA last spring. The study concerned the use of the anti-depressant Lexapro in stroke patients.

Rheumatoid arthritis (RA) is an agonizing autoimmune disorder of uncertain origin leading to chronic inflammation at the joints. RA develops in three stages. Nearly 46 million Americans or more than 21 percent of the adult population are affected by this disorder. The origin of RA is unknown but the disease can be controlled by way of new drugs exercise joint protection skills and self-management techniques.